abstract：:A Chikungunya virus (CHIKV) outbreak in Italy in 2007 spread to include the islands of the Caribbean and most of the Americas and still circulates in Europe and Africa. Florida being close in distance to the Caribbean islands experienced a CHIKV outbreak in 2014 and continues to have a few travel-related cases each ye...

journal_title：Viruses

authors： Shin D,Kang S,Smartt CT

更新日期：2020-07-29 00:00:00

abstract：:The MinION sequencer is increasingly being used for the detection and outbreak surveillance of pathogens due to its rapid throughput. For RNA viruses, MinION's new direct RNA sequencing is the next significant development. Direct RNA sequencing studies are currently limited and comparisons of its diagnostic performanc...

journal_title：Viruses

authors： Leigh DM,Schefer C,Cornejo C

更新日期：2020-07-25 00:00:00

abstract：:Endemic to West Africa and South America, mammalian arenaviruses can cross the species barrier from their natural rodent hosts to humans, resulting in illnesses ranging from mild flu-like syndromes to severe and fatal haemorrhagic zoonoses. The increased frequency of outbreaks and associated high fatality rates of the...

journal_title：Viruses

authors： Stott RJ,Strecker T,Foster TL

更新日期：2020-07-21 00:00:00

abstract：:The coronavirus disease 2019 (COVID-19) outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects almost everyone in the world in many ways. We previously predicted antivirals (atazanavir, remdesivir and lopinavir/ritonavir) and non-antiviral drugs (tiotropium and rapamycin) that may inhi...

journal_title：Viruses

authors： Kang K,Kim HH,Choi Y

更新日期：2020-07-20 00:00:00

abstract：:The Pneumoviridae family includes human metapneumovirus (HMPV) and human orthopneumovirus, which is also known as a respiratory syncytial virus (HRSV). These are large enveloped, negative single-strand RNA viruses. HMPV and HRSV are the human members, which commonly infect children. HMPV, which was discovered in 2001,...

journal_title：Viruses

authors： Diab M,Schmiedel D,Seidel E,Bacharach E,Mandelboim O

更新日期：2020-07-20 00:00:00

abstract：:Nasopharyngeal cancer (NPC) is associated with Epstein Barr virus (EBV) infection. However different viral strains have been implicated in NPC worldwide. This study aimed to detect and characterize EBV in patients diagnosed with NPC in Ghana. A total of 55 patients diagnosed with NPC by CT scan and endoscopy were age-...

journal_title：Viruses

authors： Ayee R,Ofori MEO,Tagoe EA,Languon S,Searyoh K,Armooh L,Bilson-Amoah E,Baidoo K,Kitcher E,Wright E,Quaye O

更新日期：2020-07-16 00:00:00

abstract：:Since deer were introduced into Australia in the mid-1800s, their wild populations have increased in size and distribution, posing a potential risk to the livestock industry, through their role in pathogen transmission cycles. In comparison to livestock, there are limited data on viral infections in all wildlife, incl...

journal_title：Viruses

authors： Huaman JL,Pacioni C,Forsyth DM,Pople A,Hampton JO,Carvalho TG,Helbig KJ

更新日期：2020-07-13 00:00:00

abstract：:Pteropine orthoreovirus (PRV; Reoviridae: Spinareovirinae) is an emerging bat-borne zoonotic virus that causes influenza-like illness (ILI). PRV has thus far been found only in Australia and Asia, where diverse old-world fruit bats (Pteropodidae) serve as hosts. In this study, we report the discovery of PRV in Africa,...

journal_title：Viruses

authors： Bennett AJ,Goldberg TL

更新日期：2020-07-09 00:00:00

abstract：:The neutrophil extracellular trap (ET) is a eukaryotic host defense machinery that operates by capturing and concentrating pathogens in a filamentous network manufactured by neutrophils and made of DNA, histones, and many other components. Respiratory virus-induced ETs are involved in tissue damage and impairment of t...

journal_title：Viruses

authors： Real-Hohn A,Zhu R,Ganjian H,Ibrahim N,Hinterdorfer P,Kowalski H,Blaas D

更新日期：2020-07-04 00:00:00

abstract：:Many geometric forms are found in nature, some of them adhering to mathematical laws or amazing aesthetic rules. One of the best-known examples in microbiology is the icosahedral shape of certain viruses with 20 triangular facets and 12 edges. What is less known, however, is that a complementary object displaying 12 f...

journal_title：Viruses

authors： Besson S,Vragniau C,Vassal-Stermann E,Dagher MC,Fender P

更新日期：2020-07-02 00:00:00

abstract：:The world's first natural avian-origin H6N1 influenza A virus infection case in dogs was confirmed in Taiwan in 2014. The H6N1 virus in chickens has been endemic in Taiwan since 1972. Whether the dog H6N1 virus has interspecies transmission potential is the key issue we aim to understand. Following one virus passage i...

journal_title：Viruses

authors： Tsai SK,Shih CH,Chang HW,Teng KH,Hsu WE,Lin HJ,Lin HY,Huang CH,Chen HW,Wang LC

更新日期：2020-06-30 00:00:00

abstract：:COVID-19 epidemic has been suppressed in Hungary due to timely non-pharmaceutical interventions, prompting a considerable reduction in the number of contacts and transmission of the virus. This strategy was effective in preventing epidemic growth and reducing the incidence of COVID-19 to low levels. In this report, we...

journal_title：Viruses

authors： Röst G,Bartha FA,Bogya N,Boldog P,Dénes A,Ferenci T,Horváth KJ,Juhász A,Nagy C,Tekeli T,Vizi Z,Oroszi B

更新日期：2020-06-30 00:00:00

abstract：:We recently developed a test based on the Agilent SureSelect target enrichment system capturing genomic fragments from 191 human papillomaviruses (HPV) types for Illumina sequencing. This enriched whole genome sequencing (eWGS) assay provides an approach to identify all HPV types in a sample. Here we present a machine...

journal_title：Viruses

authors： Lomsadze A,Li T,Rajeevan MS,Unger ER,Borodovsky M

更新日期：2020-06-30 00:00:00

abstract：:The Megalocytivirus genus includes three genotypes, red sea bream iridovirus (RSIV), infectious spleen and kidney necrosis virus (ISKNV), and turbot reddish body iridovirus (TRBIV), and has caused mass mortalities in various marine and freshwater fish species in East and Southeast Asia. Of the three genotypes, TRBIV-l...

journal_title：Viruses

authors： Tsai JM,Huang SL,Yang CD

更新日期：2020-06-24 00:00:00

abstract：:HIV-1 is a global health crisis that has infected more than 37 million people. Latent reservoirs throughout the body are a major hurdle when it comes to eradicating the virus. In our previous study, we found that exosomes, a type of extracellular vesicle (EV), from uninfected cells activate the transcription of HIV-1 ...

journal_title：Viruses

authors： Barclay RA,Mensah GA,Cowen M,DeMarino C,Kim Y,Pinto DO,Erickson J,Kashanchi F

更新日期：2020-06-19 00:00:00

abstract：:As more cases of COVID-19 are studied and treated worldwide, it had become apparent that the lethal and most severe cases of pneumonia are due to an out-of-control inflammatory response to the SARS-CoV-2 virus. I explored the putative causes of this specific feature through a detailed genomic comparison with the close...

journal_title：Viruses

authors： Claverie JM

更新日期：2020-06-15 00:00:00

abstract：:The human respiratory syncytial virus (hRSV) and human Metapneumovirus (hMPV) are two of the leading etiological agents of acute lower respiratory tract infections, which constitute the main cause of mortality in infants. However, there are currently approved vaccines for neither hRSV nor hMPV. Moreover, despite the s...

journal_title：Viruses

authors： Andrade CA,Pacheco GA,Gálvez NMS,Soto JA,Bueno SM,Kalergis AM

更新日期：2020-06-12 00:00:00

abstract：:The immune-suppressive effects of omega-3 (n-3) polyunsaturated fatty acids (PUFAs) on T cells have been observed via multiple in vitro and in vivo models. However, the precise mechanism that causes these effects is still undefined. In this study, we investigated whether n-3 PUFAs regulated T cell receptor (TCR) and p...

journal_title：Viruses

authors： Lim Y,Kim S,Kim S,Kim DI,Kang KW,Hong SH,Lee SM,Koh HR,Seo YJ

更新日期：2020-06-12 00:00:00

abstract：:The Australasian Virology Society (AVS) aims to promote, support and advocate for the discipline of virology in the Australasian region. The society was incorporated in 2011 after 10 years operating as the Australian Virology Group (AVG) founded in 2001, coinciding with the inaugural biennial scientific meeting. AVS c...

journal_title：Viruses

authors： Helbig KJ,Bull RA,Ambrose R,Beard MR,Blanchard H,Böcking T,Chua B,Colmant AMG,Crosse KM,Purcell DFJ,Fraser J,Hayward JA,Hamilton ST,Husain M,MacDiarmid R,Mackenzie JM,Moseley GW,Nguyen THO,Quiñones-Mateu ME,Robinson

更新日期：2020-06-06 00:00:00

abstract：:African swine fever (ASF) is a devastating disease in pigs, with no vaccines for control. The genetic manipulation of African swine fever virus (ASFV) is often tedious and time consuming. Here, we describe a method to manipulate the virus genome to produce gene deletion viruses in a much-reduced time. This method comb...

journal_title：Viruses

authors： Rathakrishnan A,Moffat K,Reis AL,Dixon LK

更新日期：2020-06-05 00:00:00

abstract：:Noroviruses are a leading cause of gastroenteritis worldwide. Although infections in healthy individuals are self-resolving, immunocompromised individuals are at risk for chronic disease and severe complications. Chronic norovirus infections in immunocompromised hosts are often characterized by long-term virus sheddin...

journal_title：Viruses

authors： Davis A,Cortez V,Grodzki M,Dallas R,Ferrolino J,Freiden P,Maron G,Hakim H,Hayden RT,Tang L,Huys A,Kolawole AO,Wobus CE,Jones MK,Karst SM,Schultz-Cherry S

更新日期：2020-06-05 00:00:00

abstract：:Bovine viral diarrhea virus (BVDV) is an important pathogen belonging to the Pestivirus genus, Flaviviridae family, which comprises viral species that causes an economic impact in animal production. Cattle are the natural host of BVDV and the main source of infection for pigs and other animal species. Due to its antig...

journal_title：Viruses

authors： de Oliveira LG,Mechler-Dreibi ML,Almeida HMS,Gatto IRH

更新日期：2020-05-31 00:00:00

abstract：:Extracellular vesicles (EVs) play an important role in intercellular communication. They are naturally released from cells into the extracellular environment. Based on their biogenesis, release pathways, size, content, and function, EVs are classified into exosomes, microvesicles (MVs), and apoptotic bodies (ApoBDs). ...

journal_title：Viruses

authors： Alqatawni A,Sharma AL,Attilus B,Tyagi M,Daniel R

更新日期：2020-05-27 00:00:00

abstract：:During flavivirus infection, some viral proteins move to the nucleus and cellular components are relocated from the nucleus to the cytoplasm. Thus, the integrity of the main regulator of the nuclear-cytoplasmic transport, the nuclear pore complex (NPC), was evaluated during infection with dengue virus (DENV) and Zika ...

journal_title：Viruses

authors： De Jesús-González LA,Cervantes-Salazar M,Reyes-Ruiz JM,Osuna-Ramos JF,Farfán-Morales CN,Palacios-Rápalo SN,Pérez-Olais JH,Cordero-Rivera CD,Hurtado-Monzón AM,Ruíz-Jiménez F,Gutiérrez-Escolano AL,Del Ángel RM

更新日期：2020-05-26 00:00:00

abstract：:This is the first record of a fish nidovirus isolated from a consignment of goldfish at the United Kingdom (UK) border. The full-length viral genome was 25,985 nt, sharing a 97.9% nucleotide identity with the Chinook salmon bafinivirus (CSBV) NIDO with two deletions of 537 and 480 nt on the ORF Ia protein. To assess t...

journal_title：Viruses

authors： Cano I,Stone D,Savage J,Wood G,Mulhearn B,Gray J,Stinton N,Ross S,Bonar M,Taylor NGH,Bateman KS,Feist SW

更新日期：2020-05-25 00:00:00

abstract：:We studied whether cytosine phosphate-guanine (CpG) recoding in a viral genome may provide oncolytic candidates with reduced infection kinetics in nonmalignant brain cells, but with high virulence in glioblastoma stem cells (GSCs). As a model, we used well-characterized CpG-recoded Zika virus vaccine candidates that p...

journal_title：Viruses

authors： Trus I,Berube N,Jiang P,Rak J,Gerdts V,Karniychuk U

更新日期：2020-05-25 00:00:00

abstract：:Influenza virus infections can lead to viral pneumonia and acute respiratory distress syndrome in severe cases, causing significant morbidity and mortality and posing a great threat to human health. Because of the diversity of influenza virus strains and drug resistance to the current direct antiviral agents, there ha...

journal_title：Viruses

authors： Zhang L,Chen J,Ke C,Zhang H,Zhang S,Tang W,Liu C,Liu G,Chen S,Hu A,Sun W,Xiao Y,Liu M,Chen X

更新日期：2020-05-18 00:00:00

abstract：:Mutations are incorporated into the genomes of RNA viruses at an optimal frequency and altering this precise frequency has been proposed as a strategy to create live-attenuated vaccines. However, determining the effect of specific mutations that alter fidelity has been difficult because of the rapid selection of the v...

journal_title：Viruses

authors： Patterson EI,Khanipov K,Swetnam DM,Walsdorf S,Kautz TF,Thangamani S,Fofanov Y,Forrester NL

更新日期：2020-05-15 00:00:00

abstract：:Environmental and agricultural pollination services by honey bees, Apis mellifera, and honey production are compromised by high levels of annual colony losses globally. The majority are associated with disease caused by deformed wing virus (DWV), a positive-strand RNA virus, exacerbated by the ectoparasitic mite Varro...

journal_title：Viruses

authors： Gusachenko ON,Woodford L,Balbirnie-Cumming K,Campbell EM,Christie CR,Bowman AS,Evans DJ

更新日期：2020-05-12 00:00:00

abstract：:Hepatitis A virus (HAV) infection is one of the major causes of acute hepatitis, and this infection occasionally causes acute liver failure. HAV infection is associated with HAV-contaminated food and water as well as sexual transmission among men who have sex with men. Although an HAV vaccine has been developed, outbr...

journal_title：Viruses

authors： Kanda T,Sasaki R,Masuzaki R,Matsumoto N,Ogawa M,Moriyama M

更新日期：2020-05-12 00:00:00

abstract：:SARS-CoV-2 enters cells using its Spike protein, which is also the main target of neutralizing antibodies. Therefore, assays to measure how antibodies and sera affect Spike-mediated viral infection are important for studying immunity. Because SARS-CoV-2 is a biosafety-level-3 virus, one way to simplify such assays is ...

journal_title：Viruses

authors： Crawford KHD,Eguia R,Dingens AS,Loes AN,Malone KD,Wolf CR,Chu HY,Tortorici MA,Veesler D,Murphy M,Pettie D,King NP,Balazs AB,Bloom JD

更新日期：2020-05-06 00:00:00

abstract：:Canine parvovirus (CPV-2) is the causative agent of haemorrhagic gastroenteritis in canids. Three antigenic variants-CPV-2a, CPV-2b and CPV-2c-have been described, which are determined by variations at residue 426 of the VP2 capsid protein. In Colombia, the CPV-2a and CPV-2b antigenic variants have previously been rep...

journal_title：Viruses

authors： Giraldo-Ramirez S,Rendon-Marin S,Ruiz-Saenz J

更新日期：2020-04-30 00:00:00

abstract：:In this review, we describe the distribution and genetic diversity of sapoviruses detected among humans, animals and the environment in African countries. Databases were searched for studies conducted in African countries and published between Jan 2005 and Mar 2019. Only studies where RT- PCR was used for initial dete...

journal_title：Viruses

authors： Makhaola K,Moyo S,Kebaabetswe LP

更新日期：2020-04-27 00:00:00

abstract：:The whole world is currently facing an unseen enemy, called coronavirus disease 2019 (COVID-19), which is causing a global pandemic. This disease is caused by a novel single-stranded enveloped RNA virus, known as the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Although huge efforts are being made to ...

journal_title：Viruses

authors： Hassan STS

更新日期：2020-04-23 00:00:00

abstract：:Potato virus Y (PVY) is the most economically important virus infecting cultivated potato (Solanum tuberosum L.). Accurate diagnosis is crucial to regulate the trade of tubers and for the sanitary selection of plant material for propagation. However, high genetic diversity of PVY represents a challenge for the detecti...

journal_title：Viruses

authors： Della Bartola M,Byrne S,Mullins E

更新日期：2020-04-23 00:00:00

abstract：:The mosquito antiviral response has mainly been studied in the context of arthropod-borne virus (arbovirus) infection in female mosquitoes. However, in nature, both female and male mosquitoes are frequently infected with insect-specific viruses (ISVs). ISVs are capable of infecting the reproductive organs of both sexe...

journal_title：Viruses

authors： Frangeul L,Blanc H,Saleh MC,Suzuki Y

更新日期：2020-04-21 00:00:00

abstract：:Viral outbreaks of varying frequencies and severities have caused panic and havoc across the globe throughout history. Influenza, small pox, measles, and yellow fever reverberated for centuries, causing huge burden for economies. The twenty-first century witnessed the most pathogenic and contagious virus outbreaks of ...

journal_title：Viruses

authors： Soman Pillai V,Krishna G,Valiya Veettil M

更新日期：2020-04-20 00:00:00

abstract：:Micro RNAs (miRNAs) are a class of small non-coding single-stranded RNA, which play an important role in modulating host-Influenza A virus (IAV) crosstalk. The interplay between influenza and miRNA interaction is defined by a plethora of complex mechanisms, which are not fully understood yet. Here, we demonstrate that...

journal_title：Viruses

authors： Sharma S,Chatterjee A,Kumar P,Lal S,Kondabagil K

更新日期：2020-04-15 00:00:00

abstract：:Interferon (IFN) regulatory factor 3 (IRF3) is the key transcription factor for the induction of IFN and antiviral genes. The absence of antiviral genes in IRF3 deficiency leads to susceptibility to a wide range of viral infections. Previously, we uncovered a function for nontranscriptional IRF3 (nt-IRF3), RLR (RIG-I-...

journal_title：Viruses

authors： Glanz A,Chawla K,Fabry S,Subramanian G,Garcia J,Jay B,Ciricillo J,Chakravarti R,Taylor RT,Chattopadhyay S

更新日期：2020-04-14 00:00:00

abstract：:Lassa mammarenavirus (LASV) is the etiologic agent of Lassa fever. In endemic regions in West Africa, LASV genetic diversity tends to cluster by geographic area. Seven LASV lineages are recognized, but the role of viral genetic determinants on disease presentation in humans is uncertain. We investigated the geographic...

journal_title：Viruses

authors： Forni D,Sironi M

更新日期：2020-04-13 00:00:00